The use of numerical exposure evaluations performed with high-resolution anatomical models has become an essential part of the safety assessment of radiofrequency (RF) fields over the last two decades, in applications from wireless communication and power transfer to wearable and implanted medical devices. This lecture reviews those applications of human anatomical models, and discusses the two important trends going forward: the first, using a wide range of anatomical models to perform in silico clinical trials and define a representative envelope of potential outcomes for the population; the second, using morphed and posed models to create a ‘digital twin’ to perform precise assessments relevant for a specific person. Montreal, Quebec, Canada, Virtual: https://events.vtools.ieee.org/m/274198